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During mastication they are enzimatically converted into thiocyanates, goitrin metabolites, that cause a competitive inhibition of the sodium/iodide symporter, thus inhibiting the thyroid hormones synthesis and possibly causing hypothyroidism [156]

However, these drugs can be expensive for the patient, even with qualifying rebates and discounts by the manufacturer, and adding them to a plan formulary may carry similar risk

When Should I Go To The Hospital For Melena

2001 Mar;16(3):542-51

LCMS analysis of the PDHc is more complex, given the two lipoylated sites on the PDHc-E2 subunit, and we were only able to reproducibly detect lipoyl moieties on K259

AZ/CSPC