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By comparing AOD 9604 with GHRH analogues and full-length growth hormone, researchers can better define pathway specificity, receptor involvement, and downstream metabolic outcomes in controlled laboratory models

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In the TRIUMPH-1 Phase 3 trial, participants on the highest dose of retatrutide lost an average of 28.3% of their body weight at 80 weeks

Whilst their primary indication remains glycaemic control, emerging evidence suggests GLP-1 receptor agonists exert effects beyond glucose metabolism