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Per the KFF 2025 Employer Health Benefits Survey, 43% of large employer plans (5,000+ employees) cover GLP-1s for weight loss, and virtually all require prior authorization

Wise LA, Willis SK, Mikkelsen EM, et al

4 A 2025 systematic review examining GLP-1 receptor agonists for depression found that several observational studies showed reduced depressive symptoms in people taking these medications, though results from randomised controlled trials were more mixed

& Nie, G

Check out common semaglutide headaches and tirzepatide side effects to know what's normal, and the symptoms to flag to your health provider

Now that we have established a basic understanding of semaglutide, we can discuss how fast it works to cause weight loss