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Two are FDA-approved specifically as injectable weight loss medications: Saxenda (liraglutide) approved in 2014, injected once daily

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Research published in Science Translational Medicine (2015) demonstrated that elevated B12 levels can alter the gene expression patterns of these bacteria, specifically downregulating genes involved in B12 synthesis within the bacterial cells

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(More information) The long-term use of certain medications, such as inhibitors of stomach acid secretion and the anti-diabetes drug, metformin, can adversely affect vitamin B 12 absorption