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Excessive presence of ROS also leads to DNA damage in sperm, which generally reduces male fertility

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(4) PLC may cleave membrane PIP into other signaling molecules, such as inositol-1,4,5-trisphosphate (IP) and diacylglycerol (DAG)

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Park B, Kim JY, Riffey OF, Walsh TJ, Johnson J, Donohoe DR