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Mild nasal irritation when intranasal routes used in published Semax/Selank research Injection site reactions for subcutaneous administration routes Generally well-tolerated in nootropic peptide literature at research doses No significant dependence or withdrawal reported in animal model studies Handling Reconstituting Melanotan II Melanotan II is supplied as a lyophilised powder and must be reconstituted before use in laboratory protocols

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Ann Oncol 26 (1): 179-85, 2015