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Patients with pre-existing diabetic retinopathy , especially those on insulin, may experience temporary worsening of retinopathy with rapid improvements in glycaemic control and should have appropriate eye monitoring

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As the competition for powerful weight loss efficacy intensifies, Roche has put forward a combination strategy using an amylin analogue to address the most significant weakness of glucagon-like peptide-1 (GLP-1) class therapies: nausea as a side effect

That said, some patients with Crohn's disease may also have type 2 diabetes or obesity , conditions for which Mounjaro is indicated

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Many researchers report the most noticeable increase in GI side effects during the first 7 to 10 days at 8mg