The incidence of SJS is estimated to be between 1.1 and 7.1 cases per million person-years.1 SJS is currently considered to be a part of bullous disease syndromes [SJS, SJS- toxic epidermal necrolysis (TEN) overlap syndrome, and TEN] in which keratinocyte cell death results in subepidermal separation
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane
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GSTs exhibit a wide intracellular distribution, being localized in mitochondria (GSTA1), cytosol (alpha, mu, pi, and zeta) and membrane-bound (MGST1) isoforms (Li et al., 2011)
In addition, As stimulates the generation of free radicals and reactive oxygen species (ROS), resulting in oxidative stress
Our bodies are consistently exposed to pollutants, toxins, and other substances that can damage our bodies