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Because patients with PD already show reduced levels of protective Trp derivatives, further restriction could exacerbate this deficit and undermine AhR-mediated signaling

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We revealed that various concentrations of the PI3K inhibitor LY294002 and Akt inhibitor MK-2206 2HCL suppressed the up-regulation of miR-146a-3p levels induced by GHK in a concentration-dependent manner (Figures 6B,C)

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