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Paul Edison, a professor of neuroscience at Imperial College London who led the study, said in a release

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Such side effects may help explain why 65 percent of people without type 2 diabetes who take a GLP-1 drug quit within a year, scientists suggested in January in JAMA Network Open

People with kidney or liver disease should consult a provider before daily supplementation, and doses above 3000 mg/day should not be taken without medical guidance

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Risk ratios (RR) for nonfatal myocardial infarction estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons