At our practice, we emphasize that GLP-1s are toolsnot magic
It is not FDA-approved, it has never been FDA-approved, and it has no approved label, no approved dose, and no authorized consumer supply
If appropriate, your provider may prescribe GLP-1 medications such as semaglutide or tirzepatide, which help reduce appetite, support portion control, and promote sustainable weight loss when combined with lifestyle changes
Structural basis of Gs and Gi recognition by the human glucagon receptor
McPhersonx PS, Kim YK, Valdivia H, Knudson CM, Takekura H, Franzini-Armstrong C, et al
A large, long-term study of semaglutide, the active ingredient in Wegovy, found that patients with obesity but without diabetes continued losing weight for 65 weeks and sustained the weight loss for up to 4 years