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The two fusion proteins were designed with either an intact C-terminal end (GLP-1 WT and GLP-1 QMP) or a truncated end lacking L585 (GLP-1 LX and GLP-1 QMP/LX) (Fig

This is a reason why GLP-1 medications work best within a broader health program that includes nutrition guidance and physical activity rather than as a standalone intervention

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This means it activates three different hormone pathways in your body that naturally regulate appetite, blood sugar, and energy metabolism

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4.1 Efficacy of GLP-1 receptor agonist therapy in SID Considering their beneficial effects on body weight, effective glycemic control, and low risk of hypoglycaemia, GLP-1 RAs may be suitable therapeutic options for SID and SIH, either as adjunctive therapy or as primary treatment