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This process is mediated by the upregulation of the C-C motif chemokine receptor 2 (CCR2), which is particularly prominent in advanced stages of PD, facilitating the recruitment of these cells to sites of neuroinflammation [103]

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From Uric Acid Metabolism to Gouty Inflammation: Model Strategies for Preclinical Research Bridging the Species Gap in Hyperuricemia and Gout Research: Humanized Mouse Models for Translational Drug Discovery Hyperuricemia and gout are becoming increasingly important areas in metabolic and inflammatory disease research

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Plasma and urine were analyzed using LC-MS and GC-MS for metabolomics and lipidomics

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