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Angiocrine hepatocyte growth factor signaling controls physiological organ and body size and dynamic hepatocyte proliferation to prevent liver damage during regeneration

doi: 10.1111/nmo.12829 53 GuYLiLYangMLiuTSongXQinXet al

Because it is wrapped in fats, it is easy on the stomach and highly bioavailable

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A recent Nature article reports a preclinical GLP-1GIPlanifibranor conjugate: a unimolecular quintuple agonist designed to combine GLP-1R/GIPR co-agonism with PPAR// agonism

Short-acting versions (taken daily) may cause sharper peaks in nausea but might be cleared from the system faster