Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider
Current understanding is limited to in vitro and animal research
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Nackapan: "If theres an actual absorbtiin problem then I thought the same problem is present utilising any b12 in your liver ." Thats what I'm not sure about