In the trial with semaglutide 1 mg and 2 mg injection for type 2 diabetes mellitus, GI events occurred more frequently among patients receiving semaglutide 2 mg injection (34%) compared to semaglutide 1 mg injection (30.8%)
Semaglutide has been shown to help patients lose as much as 15% of their body weight in 68 weeks of treatment
At 5 mg/mL, these intermediate doses work out to: 0.375 mg = 7.5 units 0.625 mg = 12.5 units 0.75 mg = 15 units The flexibility of unit-based dosing from vials makes these custom doses possible
Research published in Frontiers in Clinical Diabetes and Healthcare in 2025 found that combining GLP-1 drugs with structured exercise, especially strength training and higher protein intake, helped patients keep more muscle while losing fat
Nausea is the most frequently experienced side effect, potentially affecting a significant proportion of patients, particularly during the initial weeks of therapy and during dose escalation periods
Some weeks you will lose weight rapidly
