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A dedicated kidney trial (the FLOW study
That low (and variable) uptake is why dosing conditions matter so much and why youll see careful instructions around taking it on an empty stomach with limited water and waiting before food/other meds
Your vet may recommend gradual changes like: A lower-calorie diet More consistent activity Food puzzles to slow eating Special bedding to relieve joint pressure Tracking your dogs progress with professional support ensures weight loss is safe, comfortable, and effective
On average, the Healthy control group gained 10.5% and DN/HT group 23.0% in body weight over the treatment period, whereas semaglutide treatment resulted in 3% loss in body weight compared to study start (Figure 2I)