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Abstract Emerging evidence suggests that treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) could be an interesting treatment strategy to reduce neurological complications such as stroke, cognitive impairment, and peripheral neuropathy

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Proper hydration, a balanced diet, and gradual dose increases may help minimize symptoms

The formation of ice crystals can shear the delicate amino acid chains, and the stress of a freeze-thaw cycle often leads to irreversible degradation, rendering the peptide inactive

Fantini E, Demaison L, Sentex E, Grynberg A, Athias P