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These calcium-regulatory effects also contribute to inhibiting pulmonary vein (PV) automaticity: as a primary trigger of atrial fibrillation, PVs are modulated by GLP-1RAs, which affect PV electrical activity, ionic properties, and intracellular calcium homeostasis to suppress PV automaticity (143)

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[My kids] normally think of their mom and, Oh, the slob that writes on her computer all day. But when I had to get ready for all of these events, [to] my daughter I was like Elsa from Frozen,' she said

Severe caloric restriction can lead to muscle loss, nutritional deficiencies, and metabolic adaptations that actually make long-term weight management more difficult

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