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The Satiety and Clinical Adiposity Liraglutide Evidence (SCALE) Obesity and Prediabetes randomized, double-blind, placebo-controlled trial of 3.0 mg of once daily liraglutide achieved a mean 8.4 kg weight loss in patients with obesity without T2DM [7]

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And correspondingly, PCG-MSNs possessed the Burnauer-Emmett-Teller (BET) surface area of 262.4 m 2 g 1 , which was much smaller than that of the MSNs

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Indeed, these studies are burdened by several limitations, most importantly the small sample size and the lack of evaluation of the therapeutic effect of GSH by liver biopsy, which to date is the gold standard for the definition of steatosis and fibrosis levels