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D-Nle-Tyr-Ile- NH-(CH 2 )5-CONH2 is not expected to be highly bound to plasma proteins according to quantitative structure-activity relationship (QSAR) modeling (discussed below) and since total recovery from serum was greater than 35 %

Walter et al., 1996

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The data suggest that daily melatonin treatment can induce and sustain receptor 5HT1A mRNA expression throughout the light phase

Some research suggests DSIP helps with reducing sleep latency (the time it takes to fall asleep), enhancing sleep quality promoting slow-wave sleep and supporting the sleep-wake cycle