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Enhancing intrinsic neuronal resilience through pathways such as Nrf2ARE signaling, sirtuin activation, and the regulation of autophagy reflects a promising avenue grounded in the reinforcement of cellular homeostasis

With this in mind, the doses of Botox used medically are much lower than those that cause botulism

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Superoxide Dismutase (SOD) , the Youth Molecule, is the only antioxidant agent able to regulate the production of superoxide anion radicals, thus preventing cell oxidation and damage

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Many of these therapeutic strategies applied in CKD management have focused mainly on lifestyle changes (including dietary patterns and exercise), biotics intervention (probiotics, prebiotics, and synbiotics), and FMT (Figure 3)