Nach 72 Wochen erzielte Tirzepatid eine strkere Gewichtsabnahme (21,6 % gegenber 15,4 % des Ausgangsgewichts
As noted above, Trxs are responsible for reducing Prx back to their reduced, oxidant-scavenging state, while thioredoxin reductases (TrxRDs) keep the reduced state of Trxs using NAPDH reducing equivalents, as depicted in Figure 2
Understanding these side effects is crucial for patients and healthcare providers to effectively manage them and to ensure adherence to the treatment
If additional glycaemic control is needed, the dose may be increased to 2mg once weekly after at least 4 weeks on the 1mg dose
Researchers also suspect that the profound hormonal and metabolic changes triggered by GLP-1 drugs may play a role
10.1021/acs.chemrestox.3c00229 Chem Res Toxicol