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Products with 1-2% GHK-Cu concentration in stable formulations with appropriate pH and penetration enhancers create stronger improvements more likely persisting after treatment, while lower concentrations (0.1-0.5%) or degraded products may produce subtle temporary effects disappearing quickly upon discontinuation
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It also significantly improved systolic blood pressure, waist circumference, lipid levels, and glycemic control
Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12
PLoS One 7:e38727
(2019) Open trial of vitamin B12 nasal drops in adults with myalgic encephalomyelitis/chronic fatigue syndrome: comparison of responders and non-responders
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