By activating GLP-1 receptors, semaglutide prompts the pancreas to release more insulin and less glucagon, lowering blood sugar
It could be that, given more [observational] time, they would have gone back to their baseline weight, says Nia Schwann Mitchell, an associate professor of medicine and a medical weight management specialist at Duke University
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The medication works by mimicking the natural GLP-1 hormone, which plays multiple roles in glucose regulation and appetite control
Depending on individual response and tolerance, the dose may be increased up to a maximum of 1 mg per week
In rare cases, GLP-1based therapies have been associated with pancreatitis, a serious condition involving inflammation of the pancreas