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The N-terminal domain consisting of 80-odd residues adopts a thioredoxin-like fold and harbors the G-site, which binds glutathione with a number of highly conserved residues as well as with ionic bonds from Asp101 and Glu 131 in the adjacent subunit (Figure 4)

It also has not been approved by the European Medicines Agency or any other major health regulator in other countries

Normally, antioxidants such as glutathione, catalase, and superoxide dismutase extinguish these sparks before they cause harm

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