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42,43 Of note, Abbass et al did not control for hemoglobin A1c, lipid levels, or history of cataract surgery, which could introduce bias

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At standard doses of 1 mg or less daily, side effect rates were similar to placebo

A B12 deficiency in females can cause symptoms such as fatigue, tingling feet, or depression

Patients with high baseline HOMA-IR (insulin resistance) may experience slower initial weight loss but often show sustained improvement over 12+ weeks

The authors of this paper asserted that such complexes may prove benecial in future oral methods of administration for Epitalon [ 121 ]