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& Jutel, M

doi: 10.1093/humupd/dmz049 21 FattoriVZaninelliTHRasquel-OliveiraFSHeintzOKJainASunLet al

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Mitochondria consume about 90% of cellular oxygen through cellular respiration, resulting in a constant stream of free radicals that, if mismanaged, cause long-term oxidative stress and damage [174,175,176]