Glutathione and related enzymes in multidrug resistance
Anaerobic titration of ferrous iron into purified PCBP1 revealed an iron-binding capacity of three ferrous iron atoms per molecule of PCBP1, with a dissociation constant of 0.9 0.1 M for the first and an average of 5.8 0.3 M for the remaining two ( In human cells, PCBP1, PCBP2, and PCBP3 can be isolated in complexes with ferritin ( METALLATION OF NON-HEME IRON ENZYMES In addition to ferritin, PCBPs exhibit iron chaperone activity toward other cytosolic iron enzymes
An in vitro study by Rau et al
Establishment of senescent chondrocytes The mouse embryonic carcinoma-derived chondrogenic cell line ATDC5 was used for in vitro studies
Microbial pathogens with impaired ability to acquire host iron
Beneficial gut microbiota, including Bifidobacterium , Lactobacillaceae-associated taxa , Faecalibacterium , Roseburia , and other anaerobic fermenters, contribute directly or indirectly to SCFA production 158