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Similarly, individuals with Crohns disease or ulcerative colitis may experience compromised B12 absorption, and injections can be an effective way to address this

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A 2003 study reported telomerase expression, enzyme activity and telomere elongation in fetal fibroblast cultures

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Similarly, topiramate decreased its MDA levels and increased GSH levels in a study on the prevention of flap necrosis after plastic and reconstructive surgery ( However, in a study on the potential toxic effects of topiramate on the liver and kidney of male mice, topiramate significantly decreased the activities of the antioxidant enzymes SOD and CAT, while increasing MDA and NO levels ( In vitro study found that topiramate increased MDA, NO and ROS production in astrocytes, showing a dose-dependent negative effect (Pavone and Cardile, 2003)