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44 Semaglutide in Obese or Overweight Patients without Type 2 Diabetes Xie et al performed a systematic review of studies conducted in populations with OAO, but without T2DM, and indicated that semaglutide 2.4 mg had a significant advantage in decreasing body mass and HbA1c level, but the incidence of total AEs was also the highest and could cause hypoglycemia

Ang II has several important functions and acts as a stimulant for a variety of regulatory systems, in turn playing a pivotal role in the pathophysiological effects of RAAS [52]

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