Similarly, patients with active malignancy warrant careful consideration given theoretical concerns about angiogenic effects potentially affecting tumor growth, though preclinical evidence suggests context-dependent effects that may inhibit rather than promote tumor angiogenesis
**Shaking the vial:** Rolling gently is the correct technique
A fresh lyophilized vial reconstituted immediately before subcutaneous injection, handled correctly, gives you a much more defined dose
Keep the remaining 40mg as powder (stored frozen) for your next batch
Sarcoidosis was also considered owing to fatigue, neurological symptoms, and musculoskeletal complaints, but it could not be definitively ruled out as no chest imaging was available to assess for hilar lymphadenopathy or pulmonary involvement
A clean workspace, ideally a laminar flow hood, for controlled sterile procedures