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ROC scores for the FIB4, APRI, and NFS in clinically significant fibrosis were approximately 0.83 (95% CI 0.74-0.93, p=0.21), 0.83 (95% CI .73-94, p=0.21), and 0.78 (95% CI .67-0.89 p=0.18), for the normal ALT cohort and 0.76 (95% CI 0.70-0.83, p=0.22), 0.70 (95% CI 0.63-0.77, p=0.16), 0.71 (95% CI 0.65-0.78, p=0.18) for the elevated ALT cohort
Minimizing Peptide Degradation Degradation can occur due to exposure to heat, light, or improper pH conditions
Studies have also suggested that the increase in type I IFN production was driven by increased phosphorylation of TANK-binging kinase 1 (TBK1)
Jul 2015;73(1):37-49
doi: 10.1007/s00775-008-0342-2