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For instance, a report by the Indonesian Basic Health Research (RISKESDAS) revealed that only 30% of rural diabetes patients have access to essential medications, compared to 70% in urban areas
In addition, prebiotics decreased intestinal inflammation and leaky gut
However, case reports and observational studies have demonstrated a bidirectional relationship between antihypertensive medications and depression, indicating mood-improving effects of RAS blockers, whereas other antihypertensive agents did not ( Table 6 )