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Cyannopyrrolidine moiety interacts with S1, whereas hydroxy adamantyl interacts with the S2 subsite

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Whole cell and mitochondrial proteomics After the indicated culture conditions, cell pellets were processed as per immunoblot protocol and lysed with lysis buffer (50 mM Tris-Cl pH 7.5, 150 mM NaCl, 1 mM EDTA, 2% Triton X-100) supplemented with protease inhibitors and phosphatase inhibitors (Roche)

Accordingly, this study was developed to explore the effects of PQQ treatment on myocardial hypertrophy and the underlying mechanism of action governing any observed beneficial effects

Das A, Belagodu A, Reiter RJ, Ray SK, Banik NL