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Contrave may also benefit patients who have coexisting mild depression or low motivation, although prescribing clinicians must carefully review mental health history to ensure that bupropion is appropriate

StatPearls, online: abgerufen 14.04.26

This is not as difficult as it sounds (numerous descriptions in the literature)

We suggest sole targeting of -amyloid or tau may not be fruitful in AD as contributions from -synuclein and TDP43 significantly modify disease pathogenesisalternative disease-modifying targets are crucial

[2] - [5] Recent phase 2 clinical trial data evaluating the activity and safety of GLP-3 in subjects with type 2 diabetes demonstrate its pronounced effects on both glycemic control and body weight reduction