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The incidence of melasma was 2.7% after 12 months of follow-up, lower than expected (53%) in this high-risk population [22]

Caruso A, Cutuli VM, De Bernardis E, et al

Thats why we dont recommend products with these enhancements at this time

[15] In August 2024, the SURMOUNT-1 three-year study (176-week treatment period) found that tirzepatide reduced the risk of developing type 2 diabetes by 94% in adults with pre-diabetes and obesity or overweight

Additionally, gradual dose titration helps minimize nausea and improves long-term persistence

Its for those times when your gut or immune system needs TLC as much as your skin