Gastro-oesophageal reflux is listed as a common side effect (up to 1 in 10 people) with some GLP-1 medications, particularly during initial dose titration
Di Stefano, G., Di Lionardo, A., Galosi, E., Truini, A., & Cruccu, G
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These actions combine to increase intracellular cysteine availability for both GSH synthesis and for CBS and CSE-mediated production of hydrogen sulfide (H 2 S), which promotes persulfide formation at protein thiols, and several studies have reported inhibitory effects of H 2 S on NLRP3 activity [112, 113]
Our phentermine vs semaglutide comparison helps clarify when each medication is more appropriate and whether combining them makes sense for your situation
2004;286:R13