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At this concentration, 0.125 mL (12.5 units on a standard insulin syringe) delivers 0.25 mg
Common doses are 200 to 500 micrograms once or twice a day, for 2 to 6 weeks
The exercise-mimetic angle also deserves continued development
I assess full response at 812 weeks
Then add escalation, missed-dose, measurement, monitoring, and red-flag context