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doi:10.1016/j.biopsych.2004.11.006 McLaughlin KA, Fox NA, Zeanah CH, Sheridan MA, Marshall P, Nelson CA

Boden et al

JNCI Monographs , 2011(44), 231235

Ongoing maintenance strategies are typically necessary

(For a discussion of the timing of the cascade typically seen in experimental brain injury models and the consequences of the early, high glycolytic rate resulting in ionic pump disturbance, the reader TABLE 3-1 Initiation of Acute Secondary Events Post-TBI is referred to Hovda et al., 1995.) A series of proteases becomes activated by the increase in calcium, resulting in cytoskeletal damage and further BBB breakdown, cell injury, and generation of free radicals

Since B12 helps convert food into fuel, correcting a deficiency can reduce fatigue, making it easier to stay active, exercise regularly, and burn more calories