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Because stopping GLP-1 therapy can minimize the long-term health gains
Whilst attractive as a theory, it should, nevertheless, be borne in mind that the majority of the studies cited above have been carried out in rodents or have examined isolated islets/-cells under in vitro or ex vivo conditions, and whether a local pancreatic DPP-4/GLP-1 system plays an important role in normal human physiology or in the pharmacological effect of DPP-4 inhibitors is not clear
Rathmacher JA, et al
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Curious to see how this line of investigation evolves , especially as we continue to look beyond antifibrotics alone in IPF management
