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FIGURE 4 Hence, it is the prevailing recommendation among endocrinologists that non-pregnant individuals with PCOS exhibiting abnormal glucose regulation, irrespective of their body weight status, initiate metformin therapy promptly upon diagnosis, with a prescribed duration of treatment lasting at least 36 months

Another study that set out to evaluate DNA damage in the ovaries of women with PCOS concluded that there may be significantly less glutathione in the ovary as a result of the condition

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