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Although only three of 16 participants were female participants in the Older (postmenopausal age) group, existing literature indicates that gut microbiome characteristics differ substantially between sexes, with women typically exhibiting greater microbial richness than men (64, 65)
American Society for Metabolic and Bariatric Surgery Integrated Health Nutritional Guidelines for the Surgical Weight Loss Patient 2016 Update: micronutrients
Dosing guidelines vary by application area and individual factors
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Therefore, further studies on the development of selective inhibitors of the mitochondrial SLC1A5 variant are needed and should help to establish whether the level of the SLC1A5 variant is a predictive marker of glutamine dependency in cancer 21
