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Each compound acts on distinct hormonal pathways, and none are currently approved medicines for use in the United Kingdom

10.1107/S1399004715013012

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This program evaluated the efficacy and safety of oral semaglutide in patients with DM2 from monotherapy to insulin addition, including HbA1c and body weight reduction outcomes, in addition to other relevant efficacy and safety endpoints, as compared to both placebo and other common antihyperglycemic drugs