The observed reduction in NNT achieved by the inclusion of additional endpoints beyond the primary endpoint speaks to the limitations of a restricted definition of benefit
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Again, as long as you are using the FDA-approved medications correctly and for their on-label use, semaglutides are considered safe and effective
Nature medicine , 28(10), 20832091
A year after stopping taking weight loss drugs such as Ozempic and Wegovy, people regain on average 60% of their lost weight but beyond this, their weight regain plateaus, with individuals managing to keep off 25% of the weight lost to treatment, say researchers at the University of Cambridge
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