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The retinal damage procedure included L-NAME administration in a total dose of 5 mg/kg, which was given by retrobulbar application in each eye, with 0.5 mg/0.1 ml saline per eye

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Baseline markers may include: Fasting glucose HbA1c Lipid panels Body composition measurements when available Without baseline measurements, it becomes difficult to determine whether metabolic changes are occurring or whether dose adjustments are producing meaningful effects