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IGF-1 LR3 A modified version of insulin-like growth factor, IGF-1 LR3 has a longer half-life than endogenous IGF-1

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doi: 10.1016/j.freeradbiomed.2011.05.017 [DOI] [PMC free article] [PubMed] [Google Scholar] 203

In particular, detoxification capacity and drug metabolism can differ between individuals

The presence of intramolecular hydrogen bonds in the acid form causes it to be almost undissolved in water, whereas the inclusion of eight water-friendly groups in the dianion configuration provides some water solubility at neutral pH