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UFMylation maintains tumour suppressor p53 stability by antagonizing its ubiquitination

This hormone works in the brain and digestive system

"Smaller players will likely need to demonstrate either superior tolerability, novel indication-specific efficacy, meaningfully different dosing convenience, or combination strategies that address limitations of current agents, particularly muscle loss, rather than simply competing on weight-loss magnitude alone," says Nadolsky

Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol

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Nagra RM, Becher B, Tourtellotte WW, Antel JP, Gold D, Paladino T et al