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Perturbation of these pathways is critical to many neurological disorders (NDs) such as Alzheimers disease (AD), Parkinsons disease (PD), Multiple sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), and Cerebral ischemia, indicating their involvement in the pathogenesis and advancement of these conditions (7)

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It also increases resistance to emotional stress and acts as an antioxidant

In one of these studies (56), hyperthyroid, selenium-deficient patients were randomized to receive a block-and-replace regimen (MMI plus levothyroxine), plus 200 g/day of selenium or placebo

Avoid simultaneous use with strong acids or chelators (e.g., vitamin C or retinol serums) because they can inactivate copper peptides

TGM2 is also remarkably specific for the glutamine residues that provide the substrate for the first step in the cross-linking reaction