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Animal Model:Male Swiss-Webster mice (age 2 mo, body wt 25-30 g), a model of exercise-induced oxidative stress [2]

However, an important safety concern for the development of a SARS-CoV-2 vaccine or of antibody-based therapies is the potential risk of vaccine enhancement of the disease, also known as antibody-dependent enhancement (ADE) and enhanced respiratory disease (ERD) 23